Thermo Fisher, L13538.06, 2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate, 98%

Name: 2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate, 98%
Brand: Thermo Fisher
SKU: L13538.06

Quantity: 5 g, Unit Size: Each, 2-Succinimido-1, 1, 3, 3-tetramethyluronium tetrafluoroborate (TSTU) acts as an efficient coupling agent through rapid activation of carboxylic acids to form N-succinimidyl active esters, which react with primary amines to form carboxamides. It is effective even in the presence of water. TSTU is selective towards amines in the presence of alcoholic group. It is employed as a coupling regent in the synthesis of peptides. With amine-protected alpha-amino acids, it b

Catalog Number: L13538.06

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Amino Acids

TagsChemicals Organic compounds Organoheterocyclic compounds Pyrrolidines

CollectionsThermo Fisher Chemicals Collection — Analytical Solvents, Reagents & CoAs Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 5 g
Unit Size: Each
Applications2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate (TSTU) acts as an efficient coupling agent through rapid activation of carboxylic acids to form N-succinimidyl active esters, which react with primary amines to form carboxamides. It is effective even in the presence of water. TSTU is selective towards amines in the presence of alcoholic group. It is employed as a coupling regent in the synthesis of peptides. With amine-protected alpha-amino acids, it brings about coupling without significant epimerization. It is useful for linking of sensor molecules with amino groups to amino-functionalized AFM (atomic force microscope) tips.SolubilitySoluble in acetonitrile, DMF, chloroform, dichlorormethane and acetonitrile.NotesMoisture sensitive, Incompatible with strong oxidizing agents.

Specifications

General

CAS	105832-38-0
Chemical Name or Material	2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate
EINECS Number	000-000-0
Formula Weight	301.05
Health Hazard 1	H302-H315-H319-H335
Health Hazard 2	<b>GHS H Statement</b><br />H301-H315-H319-H335<br /> Toxic if swallowed.<br />Causes skin irritation.<br />Causes serious eye irritation.<br />May cause respiratory irritation.
Health Hazard 3	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
IUPAC Name	[dimethylamino-(2,5-dioxopyrrolidin-1-yl)oxymethylidene]-dimethylazanium;tetrafluoroborate
InChI Key	YEBLHMRPZHNTEK-UHFFFAOYSA-N
MDL Number	MFCD00077875
Melting Point	195°C to 200°C
Molecular Formula	C9H16BF4N3O3
PubChem CID	9857522
Recommended Storage	Ambient temperatures
SMILES	F[B-](F)(F)F.CN(C)C(ON1C(=O)CCC1=O)=[N+](C)C
Sensitivity	Moisture sensitive
Solubility Information	Soluble in acetonitrile,DMF,chloroform,dichlorormethane and acetonitrile.

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Thermo Fisher, L13538.06, 2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate, 98%

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