Thermo Fisher, PV5365, Predictor™ hERG Fluorescence Polarization Assay Kit

Name: Predictor™ hERG Fluorescence Polarization Assay Kit
Brand: Thermo Fisher
SKU: PV5365

Quantity: 1 Kit, Unit Size: Each

Catalog Number: PV5365

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Category

Western Blot Detection Reagents

TagsProtein Analysis Reagents Immunohistochemistry Kits and Reagents

CollectionsThermo Fisher Protein Analysis Reagents for Western Blot, ELISA & Proteomics Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 1 Kit
Unit Size: Each
The Predictor™ hERG Fluorescence Polarization Assay Kit provides a set of validated components to perform hERG channel biochemical binding studies in the absence of radioligand. The assay was designed to identify potential hERG channel blockers by producing data that accurately correlates with patch-clamp electrophysiology studies. The assay is based on the principle of fluorescence polarization where a red-shifted fluorescent tracer is displaced from the hERG channel by compounds that bind to the channel. Assay performance was validated with a panel of established hERG channel blockers. Results from the Predictor™ assay demonstrate a high correlation with those obtained from patch clamp techniques.

Specifications

General

Assay Entry	Biochemical binding
Color	Red
Detection Method	Fluorescence
Druggable Target	Ion Channels
For Use With (Equipment)	Microplate Reader
Gene Symbol	hERG
Packaging	384-well Plate
Product Type	Assay Kit
Protein Family	Ion Channels
Quantity	1 Kit
Readout	End Point
Shipping Condition	Dry Ice
System Type	Predictor™ System
Target Entry	hERG
Conjugate	Predictor hERG Tracer Red
Product Line	Predictor
Unit Size	Each

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Thermo Fisher, PV5365, Predictor™ hERG Fluorescence Polarization Assay Kit

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General

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