Description
Unit Size: 300 L
The S.U.F. is engineered for optimal oxygen mass transfer, mixing, and temperature control, and performs comparably to traditional stainless steel systems. Using traditional, fundamental engineering principles, scale-up and process development work is streamlined – offering you cost savings and efficiency.Some of the key features of the SUF include:Purpose built for resultsThe S.U.F. delivers an optimal growth environment through powerful agitation through three Rushton impellers and baffles, high gas flow rates, and efficient cooling through a higher vessel surface area. The single-use fermentor is designed to help you deliver results for your fermentation processes.Stainless steel performance, single-use benefitsThe S.U.F. has been developed on standard stainless steel fermentation design geometry (3:1 height to diameter, 5:1 turndown ratio), making scale-up and process development activities easy. The single-use format helps reduce batch turnover activities, including the time-consuming clean-in-place and sterilization-in-place cycles, which helps to decrease costs and increase productivity.High oxygen transfer with minimal liquid lossControlled, flexible delivery of gas is supplied through our unique drilled-hole sparge design. Coupled with powerful agitation for gas dispersion, the single-use fermentor enables you to optimize oxygen transfer (kLa) to meet your process needs. The innovative exhaust management and condenser systems are designed to provide reliable off-gassing and help minimize liquid loss during the fermentation process.Powerful mixing for high mass transferThe single-use fermentor delivers powerful agitation through 3 Rushton impellers and a baffled vessel. This mixing facilitates high oxygen transfer and a homogeneous reaction.Increased cooling capacityThe S.U.F.’s proven 3:1 height-to-width aspect ratio optimizes the surface area for cooling. Through this high surface area and column height, the fermentor has better cooling capacity compared to less optimal 2:1 aspect ratio culture vessel designs.Automated foam controlDepending on the fermentation and conditions, foaming may occur during the process. We’ve developed a proprietary, single-use foam-sensing probe which allows you to automate foam control and helps reduce the risk of contamination or exhaust filter failure.Highly configurableConstructed using our industry leading films (CX5-14 and Aegis5-14), our robust S.U.F. bioprocess containers maintain sterility throughout the fermentation process. The containers are highly configurable, allowing you flexibility to address specific application needs.Our open architecture approach allows you to integrate the S.U.F. with the control unit of your choice. Additionally, we offer turnkey systems, shipped as a S.U.F. and integrated controller.Available in turnkey format
• Complete mixing system with a water jacket for temperature control
• Drive shaft inserts into the BPC through the mixing drive motor and locks into the BPC agitator assembly S.U.F. BPCSupplied sterile and ready to use
• Agitator assembly is a single-use (polyethylene) impeller with a bearing/ seal assembly linked to an external mixer drive
• Gas control with drilled-hole spargers
• Exhaust management system with options for multiple vent filters based on gas flow needs
• Integrally sealed ports in the S.U.F. BPC allows for sensor probes and line sets addition
• Available in Thermo Scientific™ CX5-14 Film and Thermo Scientific™ Aegis™5-14 Film optionsSystem options:Adaptable to your needs
• Exhaust condenser unit
• Exhaust gas vent filter heater
• Integrated foam sensor
• Load cells (3)
• Cable management tree
• Process control system
• Optional electrical box for remote agitation control
• S.U.F.s require a separate external temperature control unit
• Choose an open-architecture approach or a turnkey, ready-to-use S.U.F.system
