Waters, 186006552, Intact mAb Mass Check Standard

Name: Intact mAb Mass Check Standard
Brand: Waters
SKU: 186006552

Catalog Number: 186006552

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Category

CollectionsWaters Service Parts & Kits for ACQUITY, Alliance & Arc Waters Sample Preparation: SPE, Syringe Filters & QuEChERS Waters Standards & Reagents for LC/MS, HPLC & GC

Description

Analysis of intact proteins by MS is a powerful approach for protein identification and assignment of protein modifications. The Intact mAb Mass Check Standard is a LC/MS standard used as a qualitative tool for intact mass analysis. It is an intact mouse protein purified by Protein-A with a known molecular weight, ideal for higher molecular weight intact mass measurements. It is provided in a Waters Max Recovery Vial PN 18600327c. This standard is designed to be used for routine MS optimization, system setup and performance testing.

Specifications

General

Separation Mode	Reversed Phase
Detection Method	MS
Formulation	Solid
Storage Condition	-20C (Freezer)
System Type	LCMS
Shelf Life	12 Months
Shelf life upon reconstitution	1 Week
Shipping Condition	Ambient
Type	Reference
UNSPSC	41116107
Application	Protein
Product Type	Standards
Units per Package	1 pk
Cold Chain Shipping	false

FAQs

Question: What type of molecule is the Intact mAb Mass Check Standard?

Answer:It is a Protein A-purified intact mouse monoclonal antibody with a known molecular mass.

Question: What is the primary purpose of this LC–MS standard?

Answer:It supports intact-mass instrument setup, routine mass-analysis optimization, and qualitative performance checks.

Question: How should the standard be stored, and how long is it usable after reconstitution?

Answer:Unopened material is stored at −20°C; the specified shelf life after reconstitution is one week.

Application Note

Waters Intact mAb Mass Check Standard provides a characterized intact monoclonal antibody for routine qualitative LC–MS intact-mass measurements. The Protein A-purified mouse antibody has a known molecular mass and serves as a higher-molecular-weight reference during instrument setup, mass analysis optimization, and performance monitoring. The material is supplied as a solid in a Waters Max Recovery Vial for reconstitution before analysis. It is intended for intact protein mass measurement, not for evaluating IdeS-digested antibody subunits or released glycans. Storage at −20°C preserves the unopened material under the specified conditions; the prepared standard has a limited reconstituted shelf life. Regular use can help analysts recognize changes in chromatographic recovery, detected mass, or instrument response during biopharmaceutical characterization workflows.

Ordering

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Unless otherwise stated, the minimum order amount is USD 1,000.
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