Waters, 186011345, GTxResolve 2000 Å SEC Column, MaxPeak Premier 3 μm, 4.6x30 mm Guard Cartridge 1/pk (for use with both 4.6 and 7.8 mm ID analytical columns)
Catalog Number: 186011345
Send an RFQ.
Category
Pack Size1/pk
Loading…
Waters GTxResolve 2000Å SEC Columns, MaxPeak Premier 3µm are manufactured with low adsorption MaxPeak HPS hardware and novel bridged ethylene HO-PEO particles to support high recovery analyses of 800 to 2500Å diameter GTx drugs, such as plasmids, LNPs, and larger viral vectors. This column technology provides long column lifetimes, low secondary interactions, and improved MALS sensitivity. Facilitate the development of platform multiattribute SEC assays for plasmid integrity and LNP formulations analyses as well as improved detection of ejected transgenes and aggregates related to viral vectors. The Waters DNA Vector Mixture contains 25 µg of pBR322 dsDNA vector, 25 µg of Φ174 Virion ssDNA and 2 µg uracil (void marker). This standard can be used as a proficiency and system suitability test standard for chromatography separations, such as a size exclusion separation using a widepore 2000Å particle column.
| Chemistry | SEC |
|---|---|
| Separation Mode | SEC |
| Particle Substrate | Silica |
| pH Range Min | 2.5 pH |
| pH Range Max | 8 pH |
| Temperature Limits | 60 C |
| Maximum Pressure | 2000 psi (140 Bar) |
| Endcapped | No |
| Bonding Technology | SEC |
| Silanol Activity | Low |
| Particle Shape | Spherical |
| Particle Size | 3 µm |
| Endfitting Type | Parker-style |
| Pore Size | 2000 Å |
| Format | Premier Column |
| Surface Area | 19 |
| System | UHPLC, UPLC, HPLC |
| Particle Technology | Silica |
| Technique | SEC |
| USP Classification | L33 |
| Inner Diameter | 4.6 mm |
| Length | 30 mm |
| Carbon Load | 1.2 % |
| UNSPSC | 41115709 |
| Application | Gene Therapeutics |
| Brand | GTxResolve |
| Product Type | Guards |
| Units per Package | 1 pk |
Answer:It is a 4.6 × 30 mm SEC guard containing 3 µm packing with 2000 Å nominal pores.
Answer:Yes. Waters specifies the guard for compatible 4.6 mm and 7.8 mm ID GTxResolve analytical columns.
Answer:No. It is a short upstream protection cartridge; a compatible analytical column is still needed.
The Waters GTxResolve 2000 Å SEC guard cartridge protects compatible GTxResolve analytical columns by providing a short upstream section with matching wide-pore size-exclusion packing. The guard measures 4.6 × 30 mm, contains 3 µm particles with a nominal 2000 Å pore size, and uses MaxPeak Premier low-adsorption hardware. It is specified for use with both 4.6 mm and 7.8 mm internal-diameter analytical columns in this SEC family when installed with the appropriate connector. A guard cartridge helps intercept particulates and strongly retained contaminants before they reach the analytical bed, but it does not replace sample clarification or a validated prefiltration step. Install the cartridge in the correct direction and check connector compatibility, extra-column volume and system pressure before sample analysis. Monitor for increased backpressure, distorted peaks or decreased sample recovery and replace the guard when needed. This short guard is not the full-length analytical SEC column and is supplied as one cartridge per pack.
Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:
Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.
