| Chemistry | Cyano (CN) |
|---|---|
| Separation Mode | Reversed Phase |
| Particle Substrate | Silica |
| pH Range Min | 2 pH |
| pH Range Max | 8 pH |
| Maximum Pressure | 6000 psi (415 Bar) |
| Endcapped | No |
| Silanol Activity | High |
| Particle Shape | Spherical |
| Particle Size | 5 µm |
| Endfitting Type | Parker-style |
| Pore Size | 80 Å |
| Format | Column |
| Surface Area | 220 |
| System | HPLC |
| USP Classification | L10 |
| Inner Diameter | 4.6 mm |
| Length | 250 mm |
| Carbon Load | 3 % |
| UNSPSC | 41115709 |
| Brand | Spherisorb |
| Product Type | Columns |
| Units per Package | 1 pk |
Answer:Propyl-cyano bonded groups on silica provide its reversed-phase selectivity.
Answer:It is 4.6 × 250 mm, packed with 5 µm particles having 80 Å pores.
Answer:The cyano phase corresponds to USP L10.
Waters Spherisorb Cyano (CN) is a reversed-phase HPLC column containing a propyl-cyano bonded silica stationary phase. The 4.6 × 250 mm analytical format uses 5 µm particles with 80 Å pores. Cyano functionality provides a selectivity pattern different from standard C18 and C8 phases, helping separate analytes whose retention or peak shape is unsuitable on strongly hydrophobic materials. The packing is non-endcapped and classified as USP L10, with a published pH range of 2–8. This column is configured for reversed-phase use rather than automatically interchangeable with normal-phase cyano methods.
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