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Artificial intelligence can accelerate chromatography resin selection, but it cannot infer a universally “best resin” from catalog specifications. The practical route is a closed evidence loop: gener…
AAV, plasmid DNA and mRNA cannot be purified by simply shrinking or enlarging a monoclonal-antibody platform. Their size, surface charge, topology, shear sensitivity and product-related impurities ch…
Moving from batch chromatography to periodic counter-current chromatography (PCC) changes the resin-selection question. The best batch resin is not automatically the best continuous resin: the rankin…
Selecting a chromatography resin is not a catalog-matching exercise. It is a separation-design problem: the target molecule, the impurities that must be removed, the operating window and the bioproce…
