Merck, 205281-5G, Lithium perchlorate

General description
Lithium perchlorate (LiClO₄) is a colorless lithium salt. On the crystallization from its aqueous solution, it affords lithium perchlorate trihydrate (LiClO₄.3H₂O). It can be synthesized by reacting lithium chloride with perchloric acid.
Application
Lithium perchlorate (LiClO₄) may be used as a catalyst in the synthesis of bis(indolyl)methanes.
When used as a co-catalyst, accelerates the Baylis-Hillman reaction, the coupling of α,β-unsaturated carbonyls with aldehydes.
Lithium perchlorate may be used to catalyze:
The acylation of hindered alcohols and phenols under solvent-free conditions.
1,4-Conjugate addition of O-silylated ketene acetals to hindered αβ,-unsaturated carbonyl system.
The protection of amine groups as N-Boc derivatives via tert-butoxycarbonylation.
Synthesis of α-aminophosphonates under solvent free conditions.