Merck, 22880-1L, Chloroacetyl chloride

General description
Chloroacetyl chloride is an aliphatic acid chloride.
Application
Chloroacetyl chloride was used in the synthesis of N-hydrazino acetyl-sulphonamides.
Chloroacetyl chloride may be used to prepare:
2-chloro-N-(pyridine-2-yl)acetamide via N-acylation of pyridin-2-amine
chloroacetyl cellulose by reacting with cellulose in N,N-dimethylformamide
azetobenzothiazine derivatives by reacting with 1,3-benzothiazines in the presence of a base in refluxing toluene
2-chloro-1-(3,5-diaryl-4,5-dihydropyrazol-1-yl)-ethanones by reacting with 3,5-diaryl-4,5-dihydropyrazoles
chloroacetyl isatins by reacting with isatins under microwave conditions
It acts as a linker during the grafting of pyrimethanil with chitosan.