Merck, 324890-500MG, E-64 Protease Inhibitor

Name: E-64 Protease Inhibitor
Brand: Merck
SKU: 324890-500MG

Size:500 mg, E-64 Protease Inhibitor, (2 R, 3 R)-3-(( S)-1-(4-Guanidinobutylamino)-4-methyl-1-oxopentan-2-ylcarbamoyl)oxirane-2-carboxylic acid, trans-Epoxysuccinyl-L-leucylamido(4-guanidino)butane, L- trans-3-Carboxyoxira, (2R, 3R)-3-((S)-1-(4-Guanidinobutylamino)-4-methyl-1-oxopentan-2-ylcarbamoyl)oxirane-2-carboxylic acid, trans-Epoxysuccinyl-L-leucylamido(4-guanidino)butane, L-trans-3-Carboxyoxiran-R, The E-64 Protease Inhibitor, also referenced under CAS 66701-25-5, controls the biological

Available Catalog Numbers

324890-100MG 324890-1GM 324890-1MG 324890-25MG 324890-500MG 324890-5MG

Catalog Number: 324890-500MG

Pricing

Send an RFQ.

View RFQ List

Category

Protease Inhibitors

Pack Size500 mg

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Irreversible inhibitor of cysteine proteases. Interacts with the Sn subsites of proteases. Has no action on cysteine residues in other proteins. Inhibits activation-induced programmed cell death and restores defective immune responses in HIV⁺ donors. Specific active site titrant.
Biochem/physiol Actions
Cell permeable: no
Primary Target
cysteine proteases
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
Other Notes
Matsumoto, K., et al. 1999. Biopolymers51, 99.
Sarin, A., et al. 1994. J. Immunol.153, 862.
Sarin, A., et al. 1993. J. Exp. Med. 178, 1693.
Barrett, A.J. 1982. Biochem. J.201, 189.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)

Specifications

General

UNSPSC Code	12352200
NACRES	NA.77
MDL number	MFCD00080261
SMILES string	N([C@@H](CC(C)C)C(=O)NCCCCN\C(=N/[H])\N)C(=O)[C@@H]1O[C@H]1C(=O)O
InChI	1S/C15H27N5O5/c1-8(2)7-9(20-13(22)10-11(25-10)14(23)24)12(21)18-5-3-4-6-19-15(16)17/h8-11H,3-7H2,1-2H3,(H,18,21)(H,20,22)(H,23,24)(H4,16,17,19)/t9-,10+,11+/m0/s1
InChI key	LTLYEAJONXGNFG-HBNTYKKESA-N
description	RTECS - RR0390000
assay	≥98% (HPLC)
form	solid
manufacturer/tradename	Calbiochem®
storage condition	OK to freeze
color	white
solubility	water: 20 mg/mL
shipped in	ambient
storage temp.	−20°C
Quality Level	200

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.

Merck, 324890-500MG, E-64 Protease Inhibitor

Send an RFQ.

General

Notice

More from Merck.

Superspher® 60 RP-8 LiChroCART™ 250-4

Superspher® 60 RP-select B LiChroCART™ 250-4

Aluminum chloride hexahydrate

Ninhydrin Reagent

More from Merck.

Superspher® 60 RP-8 LiChroCART™ 250-4

Superspher® 60 RP-select B LiChroCART™ 250-4

Aluminum chloride hexahydrate

Ninhydrin Reagent