Merck, 927708-100MG, 2,2,11-trimethyl-4-oxo-3,8-dioxa-5,11-diazatetradecan-14-oic acid

Name: 2,2,11-trimethyl-4-oxo-3,8-dioxa-5,11-diazatetradecan-14-oic acid
Brand: Merck
SKU: 927708-100MG

Size:100 mg, ≥95%

Available Catalog Numbers

Catalog Number: 927708-100MG

Pricing

Category

Pack Size100 mg

Description

Application
2,2,11-trimethyl-4-oxo-3,8-dioxa-5,11-diazatetradecan-14-oic acid is a heterobifunctional crosslinker useful for development of PROTAC degraders for targeted protein degradation or other bifunctional molecules in chemical biology. Incorporation of rigidity into the linker region may impact the 3D orientation of the molecules and thus ternary complex formation as well as optimization of drug-like properties. For linkers already conjugated to E3 ligase ligands, please visit our collection of Protein Degrader Building Blocks.
Other Notes
Technology Article: Degrader Building Blocks for Targeted Protein Degradation

Protein Degrader Building Blocks Portal

Crosslinkers for Bioconjugation

Specifications

Ordering

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.

More from Merck.