Merck, P6001-250G, p-Phenylenediamine

Application
p-Phenylenediamine has been used:
to evaluate its sensitization potential in vitro in langerhans-like dendritic cells and autologous T cells
to treat the dorsal sides of the ears of mice, to study its systemic immunological effects
in glycerol to coverslip coronal sections in the attempt to count Aβ plaques

Anti-fade reagent is added to the mounting medium in fluorescence microscopy to retard photobleaching of fluorescein and other fluorescent dyes.
Biochem/physiol Actions
p-Phenylenediamine causes allergic reactions with skin. It is widely used in hair dyes. It eventually forms Bandrowski′s base, which is found to be the primary cause for allergy. p-Phenylenediamine exposure results in dermatitis, urticaria and anaphylaxis. It acts as an electron donor and is known to reduce cytochrome c.
Disclaimer
Darkens in storage.