Thermo Fisher, 60210, Dynabeads™ Streptavidin Magnetic Beads

Name: Dynabeads™ Streptavidin Magnetic Beads
Brand: Thermo Fisher
SKU: 60210

Product Type: Dynabeads™ M-280 Streptavidin, Quantity: 100 mL, Unit Size: Each, Dynabeads Streptavidin Magnetic Beads are designed for high-specificity, low-background capture of target molecules with biotinylated affinity binders such as antibodies, antigens, or oligonucleotides. Available in various sizes and surface chemistries, these beads can be tailored to provide the best fit for specific application needs.Dynabeads Streptavidin Magnetic Beads are compatible with high-throughput automatio

Catalog Number: 60210

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Category

Affinity Tag Purification Resins

Pack Size100 mL

TagsMolecular Biology Reagents and Kits DNA Extraction and Purification

CollectionsThermo Fisher Molecular Biology Reagents & Kits Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Product Type: Dynabeads™ M-280 Streptavidin
Quantity: 100 mL
Unit Size: Each
Key advantages of Dynabeads Streptavidin Magnetic Beads
• ISO 13485–certified manufacturing—exceptional manufacturing control to ensure robust and consistent performance between production lots, meeting international quality standards for medical devices
• Monosized, monodispersed magnetic beads—uniform particle size provides consistent and reproducible results across applications
• Dual size options—available in 1-μm and 2.8-μm diameter specifications to accommodate diverse experimental requirements and application-specific needs
• Multiple surface chemistry options—various surface functionalization chemistries available to optimize binding efficiency and compatibility for specific applications
• Application-optimized design—size and surface chemistry combinations enable best-fit selection for targeted experimental protocols and assay requirementsPrecision-engineered manufacturing delivers exceptional control over critical bead propertiesDynabeads Streptavidin products are based on magnetic polystyrene-based beads that are covalently coupled with recombinant streptavidin, creating a robust platform for target capture and isolation using biotinylated affinity binders. Dynabeads Streptavidin product manufacturing enables exceptional precision over three critical parameters: size distribution, magnetization properties, and surface chemical characteristics. This ensures consistent performance across batches and applications, providing the reliability necessary for reproducible experimental outcomes.Optimized size selection enhances application-specific performanceThe Dynabeads Streptavidin product line offers two distinct size options, each engineered to excel in specific experimental contexts. The 1-μm beads, available in the Dynabeads MyOne series, are ideally suited for applications requiring fast reaction kinetics, slow sedimentation rates, and high sensitivity-to-capacity ratios. These smaller beads provide enhanced surface area contact and reduced gravitational settling, making them particularly valuable for sensitive detection assays.In contrast, the 2.8-μm beads, found in the Dynabeads M-270 and M-280 series, are perfect for applications demanding low background binding and reduced risk of aggregation in aggregation-prone applications. These larger beads offer even easier handling and faster magnetic separation compared to the Dynabeads MyOne series, facilitating streamlined workflow processing.Tailored surface chemistry options address diverse experimental requirementsThe Dynabeads Streptavidin product line includes two distinct surface chemistry configurations designed to optimize performance across varied experimental conditions. Hydrophobic surfaces are available in Dynabeads MyOne Streptavidin T1, Dynabeads Streptavidin for Target Enrichment, and Dynabeads M-280 Streptavidin products. These surfaces are BSA-blocked after streptavidin coupling making them ideal for high signal-to-noise applications such as immunoassays, target enrichment, and on-bead PCR for next-generation sequencing.Alternatively, hydrophilic surfaces are featured in Dynabeads MyOne Streptavidin C1, Dynabeads Streptavidin for In Vitro Transcription, and Dynabeads M-270 Streptavidin products. These surfaces contain no BSA blocking and are particularly suitable for hydrophobic targets, harsh lysis conditions, sample preparation workflows for mass spectrometry, and applications demanding low or no nuclease activity, such as on-bead reverse transcription or in vitro transcription.For researchers uncertain about which bead type best suits their application, a Dynabeads Streptavidin Trial Kit is available. It allows for side-by-side performance evaluation of different bead formulations under your specific experimental conditions, ensuring optimal selection for your research needs.ISO 13485 certification ensures scalable quality and OEM supportManufactured under ISO 13485 certification, Dynabeads Streptavidin products deliver outstanding batch-to-batch consistency. This robust quality assurance framework ensures that once customers develop an assay or workflow, they can rely on reproducible results across multiple experimental iterations. This consistency makes these versatile beads an efficient solution for applications spanning the entire spectrum from fundamental research to commercial manufacturing processes. For researchers developing commercial products or services, or those requiring larger bulk volumes, specialized support is available by emailing [email protected].

Specifications

General

Bead Type	Magnetic polystyrene-based beads covalently coupled with recombinant Streptavidin
Binding Property	490-750 pmol free biotin/mg beads
Certifications/Compliance	ISO9001 and ISO13485
Concentration	10 mg/mL
Diameter (Metric)	2.8 μm (CV < 5%)
For Use With (Application)	Immunoassays, biopanning, etc, requiring high specificity, low background binding, and ease of handling
For Use With (Equipment)	KingFisher™ Sample Purification System, DynaMag™ magnets
High-throughput Compatibility	High-throughput Compatible
Product Line	Dynabeads
Product Type	Dynabeads™ M-280 Streptavidin
Quantity	100 mL
Regulatory Status	For Research Use Only
Shelf Life	36 months from date of manufacture
Shipping Condition	Ambient Temperature
Surface Functionality	Tosylactivated hydrophobic surface blocked with BSA
Format	Beads in Suspension
Isolation Technology	Magnetic Bead
Unit Size	Each

FAQs

Question: What is the bead size and surface chemistry?

Answer:The M-280 beads are 2.8 µm magnetic particles with covalently coupled recombinant streptavidin on a hydrophobic surface.

Question: What types of molecules can be captured?

Answer:They can capture biotinylated affinity binders and targets such as antibodies, antigens and oligonucleotides.

Question: What concentration are the beads supplied at?

Answer:They are supplied at 10 mg/mL in phosphate-buffered saline with BSA and sodium azide.

Application Note

Dynabeads™ M-280 Streptavidin Magnetic Beads, 100 mL are used for high-specificity capture and magnetic separation of biotinylated molecules such as antibodies, antigens and oligonucleotides. The beads are 2.8 µm magnetic particles with recombinant streptavidin covalently coupled to a hydrophobic surface, providing a stable biotin-binding solid phase for manual or automated affinity workflows. They are supplied at 10 mg/mL in phosphate-buffered saline at pH 7.4 with BSA and sodium azide as stabilizing and preservative components. The uniform magnetic format allows bound targets to be rapidly concentrated, washed and transferred without centrifugation or filtration. Dynabeads streptavidin products can also be integrated with KingFisher sample-purification systems for higher-throughput processing. The 100 mL size is appropriate for workflows that require repeated or larger-scale biotin-streptavidin capture, including assay development, immunocapture and nucleic-acid target handling.

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

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