Merck, 48-611MAG, MILLIPLEX® Akt/mTOR Signaling Panel

General description
This panel includes key phosphoproteins from the PI3K/Akt/mTOR pathway such as Akt (pS473, pT308), mTOR (pS2448), p70 S6K, RPS6, 4E-BP1, and GSK-3α/β. These analytes regulate cell survival, growth, protein synthesis, and metabolism through coordinated phosphorylation events.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 11 analytes in cell lysate samples.

Analytes Included: Akt (pS473), Akt (pT308), GSK-3α/β (pS21/S9), mTOR (pS2448), p70 S6K (pT412), p70 S6K (pT389), p70 S6K (Total), RPS6 (pS235/S236), RPS6 (pS240/S244), RPS6 (Total), 4E-BP1 (pT37/T46)

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate™ Control Assays).
Features and Benefits
Broad coverage of the PI3K/Akt/mTOR signaling pathway
Detects multiple phosphorylation sites and total proteins
Enables pathway mapping and mechanistic studies
High multiplexing reduces sample and reagent consumption
Optimized for reproducibility and sensitivity

Legal Information
Luminex is a registered trademark of Luminex Corp
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.