Description
General description
This panel focuses on biomarkers indicative of early-stage apoptosis. It includes proteins such as cleaved PARP, caspase-9, and other initiators of programmed cell death. These analytes are essential for studying the initiation of apoptosis through intrinsic and extrinsic pathways. The panel is ideal for applications in cancer research, neurodegeneration, and evaluating cytotoxic effects of therapeutic compounds.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 7 analytes in cell lysate samples.
Analytes Included: Bcl-2 (Phospho-Ser70), Bad (Phospho-Ser112), Bax, Caspase-3 (Cleaved Asp175), Caspase-7 (Cleaved Asp198), PARP (Cleaved Asp214), Cytochrome c
Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate™ Control Assays).
Features and Benefits
Measures 7 early-stage apoptosis biomarkers in a single assay
Complements late apoptosis panels for full apoptotic pathway coverage
Ideal for studying intrinsic and extrinsic apoptotic mechanisms
High sensitivity and reproducibility
Suitable for limited sample volumes and high-throughput analysis
Legal Information
Luminex is a registered trademark of Luminex Corp
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
