Description
General description
CREB is a transcription factor activated by phosphorylation at Ser133, playing a central role in regulating gene expression in response to cellular stress, growth factors, and cAMP signaling. Measuring both phosphorylated and total CREB provides insights into transcriptional activation dynamics.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to ensure optimal performance. Simultaneously analyze 2 analytes in human, mouse, or rat cell lysate samples.
Analytes Included: CREB (Phospho-Ser133), CREB (Total)
Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate™ Control Assays).
Features and Benefits
Simultaneous detection of phosphorylated and total CREB in a single well
Enables analysis of transcription factor activation in response to cellular stimuli
High sensitivity and specificity using Luminex® xMAP®technology
Ideal for studying cAMP signaling and stress response pathways
Requires minimal sample volume and supports high-throughput workflows
Legal Information
Luminex is a registered trademark of Luminex Corp
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.