Description
General description
BAD, BID, and BIM are pro-apoptotic BH3-only proteins that initiate apoptosis by antagonizing anti-apoptotic Bcl-2 members. BCL-B functions as a pro-survival protein, contributing to the balance of apoptotic signaling.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 4 analytes in human cell lysate samples.
Analytes Included: Bcl-2, Bcl-xL, Mcl-1, NOXA/Mcl-1
Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate™ Control Assays).
Features and Benefits
Measures 4 additional Bcl-2 family proteins in a single assay
Complements Bcl-2 Family Apoptosis Panel 1 for expanded apoptosis profiling
Ideal for studying intrinsic apoptotic pathways
High sensitivity and reproducibility
Suitable for limited sample volumes and high-throughput analysis
Legal Information
Luminex is a registered trademark of Luminex Corp
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.