Description
General description
Src family kinases (BLK, FGR, FYN, HCK, LCK, LYN, SRC, YES) are non-receptor tyrosine kinases involved in signal transduction for cell proliferation, differentiation, and immune responses. Phosphorylation at conserved tyrosine residues within their activation loops indicates kinase activation.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 8 analytes in cell lysate samples.
Analytes Included: BLK (pY389), FGR (pY412), FYN (pY420), HCK (pY411), LCK (pY394), LYN (pY397), SRC (pY419), YES (pY426)
Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate™ Control Assays).
Features and Benefits
Simultaneous detection of 8 phosphorylated Src family kinases
Comprehensive profiling of tyrosine kinase activity
Ideal for cancer, immune, and signal transduction research
High-throughput format reduces assay time and cost
Robust performance with minimal sample input
Legal Information
Luminex is a registered trademark of Luminex Corp
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.