Merck, 14-440, PKA Protein, Recombinant, 10 µg

General description
Research area: Cell Signaling

Product Source: Expressed in E.coli BL21 (DE3) pLysS cells Recombinant human full length PKA, catalytic subunit type alpha, untagged Protein kinase A (PKA) is a serine protein kinase and heterotetrameric holoenzyme that targets serine and threonine residues.
PKA
Recombinant human full length PKA, catalytic subunit type alpha, untagged
Biochem/physiol Actions
Protein Target: PKA; Target Sub-Family: AGC. Protein kinases are vital for integrating signaling networks within eukaryotic cells. In Hedgehog-responsive cells, PKA is crucial for regulating proliferation and fate determination by influencing Hedgehog signaling transduction. PKA has numerous targets that are linked to adhesion or migration.
Packaging
Also available in 250 µg size --call for pricing and availability and reference catalog number 14-440M when ordering the 250 µg size.
Also available in 10 μg size and in bulk
Physical form
Phosphocellulose P11 chromatography
Preparation Note
1 year at -70°C
Analysis Note
routinely evaluated by phosphorylation of Kemptide substrate in vitro
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Replaces: 14-114
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.