Merck, 14-720, FAK Protein, active, 10 µg
Size:10 μg, Active, N-terminal 6His-tagged, recombinant, human FAK, amino acids 411-686, for use in Kinase Assays.
Available Catalog Numbers
| UNSPSC Code | 12352202 |
|---|---|
| NACRES | NA.32 |
| eCl@ss | 32160405 |
| biological source | human |
| Quality Level | 100 |
| Gene Information | human ... PTK2(5747) |
| product line | Upstate® |
| specific activity | (For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.) |
| mol wt | Mw 35.5 kDa |
| purified by | (Ni2+/NTA-agarose) |
| species reactivity | human |
| manufacturer/tradename | Upstate® |
| technique(s) | activity assay: suitable (kinase) |
| accession no. | (FUNCTION: SwissProt: Q05397 # Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. ) |
| NCBI accession no. | NM_005607.3 |
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| recombinant |
|---|
| expressed in baculovirus infected Sf21 cells |
| UniProt accession no. | Q05397 |
|---|
| relevant disease(s) | obesity; metabolic disorders |
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