Merck, 14-548, MSK1 Protein, active, 10 µg

Name: MSK1 Protein, active, 10 µg
Brand: Merck
SKU: 14-548

Size:10 μg, Active, N-terminal His6-tagged recombinant human MSK1 residues 2-end, for use in Kinase Assays.

Available Catalog Numbers

14-1048 14-1057 14-1058 14-1067 14-1109 14-1121 14-155 14-173 14-197 14-197M 14-198 14-249 14-251 14-251M 14-276 14-276M 14-278 14-279 14-306 14-306M 14-309 14-314 14-314M

Description

General description
MSK1
N-terminal His6-tagged recombinant human MSK1 residues 2-end
Application
Research Category
Metabolism
Research Sub Category
Cardiovascular Disease

Metabolic Disorders
Biochem/physiol Actions
Protein Target: MSK1
Target Sub-Family: AGC
Packaging
Also available in 10 μg size and in bulk
Also available in 250 µg size --call for pricing and availability and reference catalog number 14-548M when ordering the 250 µg size.
Physical form
Ni²⁺/NTA-agarose
Preparation Note
6 months at -20°C
Analysis Note
routinely evaluated by phosphorylation of Crosstide
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Specifications

General

UNSPSC Code	12352202
NACRES	NA.32
eCl@ss	32160405
biological source	human
Quality Level	100
Gene Information	human ... RPS6KA5(9252)
product line	Upstate®
specific activity	(For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.)
mol wt	Mw 94 kDa
purified by	(Ni2+/NTA-agarose)
species reactivity	human
manufacturer/tradename	Upstate®
technique(s)	activity assay: suitable (kinase)
accession no.	(FUNCTION: SwissProt: O75582 # Serine/threonine kinase required for the mitogen or stress-induced phosphorylation of the transcription factors CREB (cAMP response element-binding protein) and ATF1 (activating transcription factor-1). Essential role in the control of RELA transcriptional activity in response to TNF. Directly represses transcription via phosphorylation of ′Ser-1′ of histone H2A. Phosphorylates ′Ser-10′ of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF), which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. May also phosphorylate ′Ser-28′ of histone H3. Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 14 (HMG-14). )

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.

Merck, 14-548, MSK1 Protein, active, 10 µg

General

Notice

Send an RFQ.

More from Merck.

Superspher® 60 RP-8 LiChroCART™ 250-4

Superspher® 60 RP-select B LiChroCART™ 250-4

Aluminum chloride hexahydrate

Ninhydrin Reagent