Merck, 14-602, PI3 Kinase (p110α/p85α) Protein, active, 20 µg

General description
Product Source: Coexpressed by baculovirus in Sf21 insect cells
Research area: Cell signaling

Protein Target: PI3Kα/p85α Target Sub-Family: PI3K/PI4K

Complex of N-terminal His6-tagged recombinant full-length human p110α and untagged, recombinant, full length, human p85α
Application
PI3 Kinase (p110α/p85α) Protein has been used in in vitro kinase assay.
Biochem/physiol Actions
Phosphoinositide 3-kinases (PI3Ks) are enzymes that play a crucial role in cell signaling. They are responsible for activating signaling pathways that regulate important cellular processes such as cell survival, proliferation, protein synthesis, cell metabolism, cytoskeletal rearrangements, and vesicle trafficking. PI3Ks exhibits both lipid kinase activity (phosphorylation of inositol ring in phosphatidylinositol (PtdIns) lipids) and protein kinase activity (including autophosphorylation).
Packaging
Also available in 250μg size as catalog # 14-602M - Call for pricing and availability.
Physical form
Ni²⁺/NTA-agarose
Preparation Note
6 months at -70°C
Analysis Note
routinely evaluated by PIProfiler
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.