Merck, 14-746M, Src (1-530) Protein, active, 250 µg

Name: Src (1-530) Protein, active, 250 µg
Brand: Merck
SKU: 14-746M

Size:250 μg, Active, N-terminal 6His-tagged, recombinant, human Src, amino acids 1-530, expressed by baculovirus in Sf21 insect cells. For use in Kinase Assays.

Available Catalog Numbers

14-1048 14-1057 14-1058 14-1067 14-1109 14-1121 14-155 14-173 14-197 14-197M 14-198 14-249 14-251 14-251M 14-276 14-276M 14-278 14-279 14-306 14-306M 14-309 14-314

Description

General description
N-terminal 6His-tagged, recombinant, human Src, amino acids 1-530, expressed by baculovirus in Sf21 insect cells.
Product Source: Expressed by baculovirus in Sf21 insect cells.
The mutant form of Src (Src, 1-530) has been identified in cases of advanced colon cancer. This truncating mutation generates an open active form of Src that has been found to be transforming, tumorigenic and metastasis promoting.
Application
Research Category
Metabolism
Research Sub Category
Cardiovascular Disease

Metabolic Disorders
Biochem/physiol Actions
Protein Target: Src
Target Sub-Family: TK
Packaging
Also available in 10 μg size (cat#14-746) and in bulk (cat# 14-746-K).
Physical form
50mM Tris-HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution
Ni²⁺/NTA-agarose
Preparation Note
6 months at -70°C from date of shipment.
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
GenBank is a registered trademark of United States Department of Health and Human Services
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Specifications

General

UNSPSC Code	12352202
NACRES	NA.32
eCl@ss	32160405
biological source	human
recombinant	expressed in baculovirus infected Sf21 cells
mol wt	Mw 61.7 kDa
manufacturer/tradename	Upstate®
technique(s)	activity assay: suitable (kinase)
GenBank accession no.	K03218
UniProt accession no.	P05480 (mouse)
Quality Level	100
Gene Information	human ... SRC(6714)

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.