Merck, 05-168, Anti-TNFα Antibody, clone MPG-XT3

Name: Anti-TNFα Antibody, clone MPG-XT3
Brand: Merck
SKU: 05-168

Size:1 mg, clone MPG-XT3, Upstate®, from rat

Available Catalog Numbers

05-0280 05-0300 05-0370 05-0390 05-0400 05-0410 05-0500 05-0535 05-0604 05-0760 05-0810 05-0860 05-0900 05-1000 05-1000X 05-1003 05-101 05-104 05-1044 05-1047 05-1049 05-1050 05-1050X

Description

General description
17 kDa
The concentration of antibody needed to neutralize the bioactivity of TNF-α will depend on the cell type, the incubation conditions, and the biological response studied.
Immunogen
Recombinant murine TNF-α
Application
Research Category
Signaling
Research Sub Category
Growth Factors & Receptors
This Anti-TNFalpha Antibody, clone MPG-XT3 is validated for use in NEUT for the detection of TNFα.
Biochem/physiol Actions
mouse TNF-α; does not recognize human or rat TNF-α
Physical form
0.01M Tris-glycine, 0.15M NaCl, pH 7.4
DEAE chromatography
Format: Purified
Preparation Note
2 years at -20°C
Analysis Note
routinely used to neutralize 50% of the cytotoxic effect of recombinant mouse TNF-α on actinomycin D treated L929 cells.
Other Notes
Replaces: 04-1114
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Specifications

General

UNSPSC Code	12352203
NACRES	NA.41
eCl@ss	32160702
isotype	IgG1
biological source	rat
conjugate	unconjugated
antibody form	purified immunoglobulin
antibody product type	primary antibodies
clone	MPG-XT3, monoclonal
species reactivity	mouse
manufacturer/tradename	Upstate®
technique(s)	neutralization: suitable
NCBI accession no.	NM_000594.2
UniProt accession no.	P01375
shipped in	dry ice
target post-translational modification	unmodified
Quality Level	100
Gene Information	human ... TNF(7124)

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