Merck, 05-1113, Anti-Harmartin (TSC1) Antibody

General description
Approx. 160 kDa
Harmartin is the gene product of tuberous sclerosis-1 (TSC1). It is thought to have a tumor suppression function and also augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination.
Immunogen
Recombinant protein from human Harmartin
Application
Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected Harmartin in human skin tissue, melanocytes.
Research Category
Signaling
Research Sub Category
PI3K, Akt, & mTOR Signaling
This Anti-Harmartin (TSC1) Antibody is validated for use in WB, IH(P) for the detection of Harmartin (TSC1).
Biochem/physiol Actions
This antibody recognizes Harmartin
Physical form
Ascites fluid. Liquid. Contains no preservative.
Unpurified ascites fluid
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.
Analysis Note
Control
NIH/3T3 cell lysate
Evaluated by Western Blot in NIH/3T3 cell lysate.
Western Blot Analysis: 1:500 dilution of this antibody detected Harmartin in 10 µg of NIH/3T3 cell lysate.
Other Notes
Replaces: 04-426
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.