Merck, 05-368MG, Anti-phospho-Ser/Thr-Pro MPM-2 Antibody

Name: Anti-phospho-Ser/Thr-Pro MPM-2 Antibody
Brand: Merck
SKU: 05-368MG

Size:1 mg, clone MPM-2, Upstate®, from mouse

Available Catalog Numbers

05-0280 05-0300 05-0370 05-0390 05-0400 05-0410 05-0500 05-0535 05-0604 05-0760 05-0810 05-0860 05-0900 05-1000 05-1000X 05-1003 05-101 05-104 05-1044 05-1047 05-1049 05-1050 05-1050X

Description

General description
This antibody recognizes a variety of proteins that are phosphorylated during mitosis.
Upon entry into M (Mitosis) phase, many proteins are phosphorylated either directly or indirectly by M-phase-promoting factor (MPF). The MPM2 monoclonal antibody binds to a phospho amino acid-containing epitope (peptides containing LTPLK and FTPLQ domains) present on more than 50 proteins of M-phase eukaryotic cells.
varies depending on the protein detected
Immunogen
Mitotic human HeLa cell cytosolic lysate
Application
Detect phospho-Ser/Thr-Pro MPM-2 also known as Mitotic protein #2 with Anti-phospho-Ser/Thr-Pro MPM-2 Antibody (Mouse Monoclonal Antibody), that has been demonstrated to work in ELISA, IHC, IP & WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair
Biochem/physiol Actions
Recognizes phosphorylated serines or threonines when followed by a proline.
Physical form
Format: Purified
Protein G Purified
Protein G Purified immunoglobulin in Protein G Purified immunoglobulin in mouse IgG in 1.0 mL PBS containing no preservatives.
Preparation Note
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Analysis Note
Control
Colcemid-treated HeLa (lane 2) cell lysates, A431 mitotic cells fixed with 3.7% paraformaldehyde
routinely evaluated in immunoblot on colcemid treated human HeLa carcinoma cells
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Specifications

General

UNSPSC Code	12352203
NACRES	NA.41
eCl@ss	32160702
isotype	IgG1
biological source	mouse
antibody form	purified immunoglobulin
antibody product type	primary antibodies
clone	MPM-2, monoclonal
species reactivity	vertebrates
manufacturer/tradename	Upstate®
technique(s)	ELISA: suitable
shipped in	wet ice
Quality Level	100
Gene Information	human ... FOXM1(2305)

Ordering

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